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| Valente,P.C.L.G.; Couto,R.M.; Gamba,C.O.; Vasconcelos,A.V.; Leme,F.O.P.; Ecco,R.; Paes,P.R.O.. |
| ABSTRACT A 20-year-old unneutered male poodle presented prostration, apathy, staggering gait, lack of appetite and tick infestation. The dog was diagnosed with a Sertoli cell tumor in an undescended testicle by cytological, histopathological and immunohistochemical tests. Pancytopenia with moderate nonregenerative anemia, leukopenia and severe thrombocytopenia were detected in the complete blood count. Cytological and histopathological evaluation of the bone marrow revealed a cellularity of 30%, with erythroid (59%), lymphoid (40%) and mast cells (1%), and an absence of granulocytic, monocytic and megakaryocytic lineage cells. In post-mortem examinations, changes related to hemostatic disorders were found. The absence of microorganisms in molecular tests... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Hyperestrogenism; Pancytopenia. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000100095 |
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| Teixeira,N.C.T.; Bicalho,A.P.C.V.; Vasconcelos,A.V.; Horta,R.S.; Cunha,R.M.C.; Lavalle,G.E.. |
| ABSTRACT Metronomic chemotherapy consists of an anticancer modality treatment. It is applicable in patients at an advanced stage, with the objective of increasing overall survival. The aim of this study was to report an anal sac apocrine carcinoma case in a dog with lymph node metastasis treated with metronomic chemotherapy sequential to surgery and conventional chemotherapy using gemcitabine and carboplatin. Metronomic chemotherapy was associated with cyclooxygenase-2 (COX-2) inhibitors, due to strong tumor COX-2 immunohistochemistry expression. Metronomic chemotherapy was initiated with cyclophosphamide, but it was replaced by lomustine, also in metronomic dosage, due to adverse effects. Treatment showed effectiveness, since the patient's overall... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Oncology; Angiogenesis inhibitor; Cyclophosphamide; Lomustine. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000400913 |
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